Covid 19 News & Insights

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COVID19 antibodies

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for the latest Covid-19 news, updates and clinical insights to better understand Covid-19’s impact on patient health.

COVID-19 Viral Load Rebound Can Occur After VV116, Nirmatrelvir-Ritonavir

HealthDay News — For patients with mild-to-moderate COVID-19, viral load rebound and symptom rebound can occur after a standard five-day course of treatment with VV116 or nirmatrelvir-ritonavir, according to a study published online March 13 in JAMA Network Open. Zhitao Yang, M.D., from Ruijin Hospital in Shanghai, and colleagues conducted a randomized clinical trial involving…

Burden of Neurologic Diagnoses Reduced After COVID-19 vs Influenza

HealthDay News — Adults have fewer health care encounters for neurologic diagnoses over the year following hospital-based care for COVID-19 versus influenza, according to a study published online March 20 in Neurology. Adam de Havenon, M.D., from Yale University in New Haven, Connecticut, and colleagues examined the burden of neurologic health care and incident neurologic…

Moderna’s New COVID-19 Vaccine Elicits Strong Immune Response in Phase 3 Trial

Positive results were observed in a phase 3 trial evaluating Moderna’s next-generation COVID-19 vaccine, mRNA-1283. The phase 3 NextCOVE study (ClinicalTrials.gov Identifier: NCT05815498) compared the safety, reactogenicity, relative vaccine efficacy and immunogenicity of mRNA-1283 to Moderna’s licensed COVID-19 vaccine, Spikevax® (mRNA-1273.222). The randomized, observer-blind, active-controlled study enrolled approximately 11,400 participants aged 12 and older.  Findings…

Rise in Outpatient Visits After COVID-19 Highlights Persistent Effects of Infection

The use of outpatient care services among veterans was found to significantly increase within the first month of COVID-19 diagnosis, highlighting the persistent effects of COVID-19 on health care resources. These findings were published in JAMA Network Open. Researchers conducted a retrospective cohort study to compare outpatient health care use across 6 categories of care…

No Elevated Risk for Stroke Identified After COVID-19 Bivalent Vaccine Receipt

HealthDay News — For Medicare beneficiaries aged 65 years and older, there is no evidence of elevated stroke risk immediately after vaccination with either brand of the COVID-19 bivalent vaccine, according to a study published in the March 19 issue of the Journal of the American Medical Association. Yun Lu, Ph.D., from the U.S. Food…

FDA Grants Emergency Use of Pemgarda for Pre-Exposure Prophylaxis of COVID-19

The Food and Drug Administration (FDA) has granted Emergency Use Authorization (EUA) to Pemgarda™ (pemivibart), a long-acting monoclonal antibody, for the pre-exposure prophylaxis of COVID-19 in adults and adolescents 12 years of age and older weighing at least 40 kg. The treatment is authorized for patients who are not currently infected with SARS-CoV-2 and have…

Paxlovid Lowers COVID-19 Hospitalization Risk Even in Vaccinated Patients

Paxlovid (nirmatrelvir-ritonavir) provides protection against hospitalization in high-risk adults with COVID-19, including those who are vaccinated, according to a study in Clinical Infectious Diseases. The retrospective analysis sought to estimate the stepwise benefit of monovalent vaccination and Paxlovid for preventing COVID-19 hospitalization. Data were obtained from the Cosmos dataset, which included more than160 million individuals…

Data From COVID-19 Pandemic Reveals High Rates of Asymptomatic RSV in Pregnancy

Asymptomatic respiratory syncytial virus (RSV) infection was more frequently identified among pregnant women between 2021 and 2023, likely due to changes in testing practices related to the COVID-19 pandemic. However, severe RSV outcomes were uncommon, indicating pregnancy is not a risk factor for severe disease. These findings were published in Open Forum Infectious Diseases. Researchers…

Children With SCD More Vulnerable to Severe COVID-19 Disease

A study published in Pediatric Blood & Cancer found that children with sickle cell disease (SCD) were highly vulnerable to severe disease with SARS-CoV-2 infection.  SCD is a chronic disease characterized by lifelong morbidity. Following the first appearance of SARS-CoV-2 in the United States in 2020, studies have found that adult patients with SCD who…